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New information reveals optimum timing for percutaneous coronary intervention in TAVR sufferers



New information reveals that percutaneous coronary intervention (PCI) might be safely carried out earlier than, throughout, or after transcatheter aortic valve substitute (TAVR) for sufferers with steady coronary artery illness (CAD). The outcomes from the evaluation have been offered at the moment on the Society for Cardiovascular Angiography & Interventions (SCAI) 2024 Scientific Classes.

For these with CAD, PCI and TAVR are sometimes required to revive blood movement. Many clinicians desire to conduct PCI earlier than TAVR as a result of potential issues that might happen through the substitute process. Nevertheless, the optimum timing for PCI in sufferers present process TAVR is debatable.

The evaluation included 49,344 sufferers with steady CAD who underwent PCI earlier than (84.7%), after (1.3%), or concurrently (14%) with TAVR utilizing the Sapien 3 (S3) platform balloon expandable bioprosthesis. The evaluation was performed utilizing the TVT Registry and Medicare linkage between 2015 and 2024.

In a propensity-matched evaluation, the composite of all-cause mortality and stroke have been related in three teams at three years of follow-up. The authors famous that as a result of small numbers of sufferers present process PCIs after the TAVR, after they in contrast simply the 2 different teams (earlier than and concomitant PCIs), PCI carried out earlier than TAVR had a slight benefit over concomitant PCI with TAVR at three years (P=0.012).

These findings are thrilling as they barely differ from beforehand revealed registry information. We consider this information will instill confidence and supply supporting proof for a lot of physicians and coronary heart groups to make selections relating to the timing of PCI in sufferers present process TAVR.”


Abhijeet Dhoble, MD, MPH, FACC, FSCAI, heart specialist at College of Texas Well being Science Heart at Houston, and lead creator of the research

Session particulars:

  • “Timing of Percutaneous Coronary Intervention in Conjunction with Transcatheter Aortic Valve Substitute with Balloon Expandable Valves in america”
  • Friday, Could 3, 2024; 3:14-3:21 PM PT
  • Lengthy Seashore Conference Heart, 104A, First Degree
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