As we mark Lyme Illness Consciousness Month this Might, HHS is proud to have a good time the 10 groups taking part in Part 2 of the LymeX Diagnostics Prize. The final word aim of HHS and the Steven & Alexandra Cohen Basis’s LymeX Innovation Accelerator (LymeX) competitors is to nurture the event of diagnostics towards Meals and Drug Administration assessment.
The present two-tier antibody testing system—initially developed in 1994 for illness surveillance, not as a stand-alone diagnostic take a look at—depends on the presence of antibodies and might solely be used precisely 4 to 6 weeks after the affected person turns into contaminated.
Accelerating innovation via money prizes and skilled sources
By September 2023, ten groups are taking part within the Part 2 digital accelerator, which affords entry to digital studying, mentorship, biorepository subject material experience, and networking alternatives. With prior work in areas starting from sepsis to genetic sequencing and glycomics, the accelerator cohort is making use of a broad vary of experience to their proposed next-generation diagnostics.
By utilizing a prize competitors mannequin, the LymeX Diagnostics Prize affords money prizes alongside a variety of non-monetary sources. The competitors is designed to stimulate the marketplace for Lyme illness diagnostics by serving to entrants overcome diagnostic improvement obstacles with prize funds and technical help—whereas additionally fostering cross-disciplinary collaboration.
Bettering testing accessibility is necessary to enhancing affected person outcomes, and groups are already starting to contemplate the difficulty with the assistance of medical research and machine design sources. Over the summer season, the cohort will take part in roundtable discussions with sufferers and clinicians as they refine their ideas.
The LymeX Diagnostics Prize is setting a brand new bar for innovation in illness diagnostics. If exams are efficiently validated, the cohort’s work might assist enhance Lyme illness therapy general—in addition to exams for different infectious ailments.
Wanting forward: Knowledgeable judging panel to convene in October 2023
Following the accelerator, the cohort will submit idea papers that element answer refinement, medical and affected person enter, and a roadmap from lab to market.
The competitors judging panel—composed of specialists throughout biology, medical and know-how translation, affected person expertise and advocacy, diagnostic science and know-how, exponential innovation, and ethics—will consider eligible submissions in response to official Part 2 analysis standards. Based mostly on the judges’ evaluations, they’ll suggest as much as 5 Part 2 winners of the LymeX Diagnostics Prize.
The Steven & Alexandra Cohen Basis has made a beneficiant $10 million pledge to the LymeX Diagnostics Prize. HHS and the Steven & Alexandra Cohen Basis awarded $1 million in Part 1 of the LymeX Diagnostics Prize, with $9 million in further LymeX prizes projected to be out there in future phases, together with Part 2. A collection of accelerator sources will likely be made out there to the general public on the competitors web site to help broader innovation in Lyme illness diagnostics and therapy.
To obtain all Part 2 updates, subscribe to the LymeX Diagnostics Prize publication and comply with @Lyme_X on Twitter.